Type III collagen mutations and cerebral aneurysms.
نویسندگان
چکیده
منابع مشابه
Type III Collagen Deficiency in Saccular Intracranial Aneurysms
Background and Purpose—We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a red...
متن کاملCollagen deficiency in cerebral aneurysms.
13. Gautier JC: Oral contraceptives and arterial strokes. Clinical data and a possible mechanism, in Greenhalgh RM, Rose FC: Progress in Stroke Research 2. London, Pitman Medical, 1983, pp 115-118 14. Mas JL, Goeau C, Bousser MG, Chiras J, Verret JM, Toubol PJ: Spontaneous dissecting aneurysms of the internal carotid and vertebral arteries—Two case reports. Stroke 1985; 16:125-129 15. Mills P, ...
متن کاملImmunohistochemical study of type III collagen expression during pre and post-natal rat skin morphogenesis
Objective(s):Skin extracellular matrix, which contains type I and type III collagens, is involved in skin development. The aim of this study was to investigate type III collagen distribution pattern as well as its changes during pre and post-natal skin morphogenesis in rats. Materials and Methods: Ventral skins of Wistar rat embryos at different stages from 10 to 20 gestational day (E10-E20) a...
متن کاملType III collagen deficiency in saccular intracranial aneurysms. Defect in gene regulation?
BACKGROUND AND PURPOSE We sought to determine whether there are mutations in the COL3A1 gene in patients with saccular intracranial aneurysms with a type III collagen deficiency and whether there is an association between a marker in the COL3A1 gene and saccular intracranial aneurysms. One of the heritable factors possibly involved in the pathogenesis of saccular intracranial aneurysms is a red...
متن کاملA new platelet receptor specific to type III collagen. Type III collagen-binding protein.
Platelet interaction with type III collagen is mediated by several platelet receptors that recognize specific sequences in collagen. We previously described an octapeptide KP*GEP*GPK within the alpha(1)III-CB4 fragment that binds to platelets and specifically inhibits platelet aggregation induced by type III collagen. In this study, we demonstrated that the octapeptide prevented platelet contac...
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ژورنال
عنوان ژورنال: Stroke
سال: 1989
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.20.10.1432